Mayoral Elections - November 8, 2022
17 of the largest 100 cities by population will have elections for mayor on the same day as the 2022 general election. Population rankings are based on July 1, 2021 Census Bureau population estimates. They are for the city itself, not the associated metropolitan area.
| City | State | Rank | Population |
| Los Angeles | CA | 2 | 3,849,297 |
| San Jose | CA | 10 | 983,489 |
| Austin | TX | 11 | 964,177 |
| Washington | DC | 23 | 670,050 |
| Louisville | KY | 28 | 628,594 |
| Raleigh | NC | 41 | 469,124 |
| Long Beach | CA | 43 | 456,062 |
| Oakland | CA | 45 | 433,823 |
| Anaheim | CA | 55 | 345,940 |
| Lexington | KY | 59 | 321,793 |
| Corpus Christi | TX | 60 | 317,773 |
| Santa Ana | CA | 62 | 309,441 |
| Irvine | CA | 64 | 309,031 |
| Chula Vista | CA | 77 | 277,220 |
| North Las Vegas | NV | 79 | 274,133 |
| Reno | NV | 82 | 268,851 |
| Laredo | TX | 87 | 256,153 |
